Which strain of Escherichia coli is known for causing Hemolytic Uremic Syndrome in children?

The strain of Escherichia coli known for causing Hemolytic Uremic Syndrome (HUS) in children is O157:H7. This particular strain is a Shiga toxin-producing E. coli (STEC), which can lead to severe gastrointestinal symptoms and complications, notably HUS, which is characterized by kidney failure, hemolytic anemia, and low platelet count.

The reason O157:H7 is of particular concern in food safety is due to its prevalence in outbreaks linked to contaminated food sources, such as undercooked meat and unpasteurized dairy products. The ability of O157:H7 to produce toxins that can damage blood vessels and lead to systemic complications makes it significantly more dangerous, especially for vulnerable populations like children.

Other strains such as O26, O111, and O145 can also cause foodborne illness and may be associated with Shiga toxin production, but O157:H7 is the most recognized strain linked to HUS, particularly in pediatric cases. Knowledge of this strain is vital for food handlers to prevent outbreaks and ensure food safety practices are in place.